Tamoxifen mechanically reprograms the tumor microenvironment via HIF‐1A and reduces cancer cell survival

The tumor microenvironment is fundamental to cancer progression, and the influence of its mechanical properties is increasingly being appreciated. Tamoxifen has been used for many years to treat estrogen‐positive breast cancer. Here we report that tamoxifen regulates the level and activity of collag...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:EMBO Rep
Päätekijät: Cortes, Ernesto, Lachowski, Dariusz, Robinson, Benjamin, Sarper, Muge, Teppo, Jaakko S, Thorpe, Stephen D, Lieberthal, Tyler J, Iwamoto, Kazunari, Lee, David A, Okada‐Hatakeyama, Mariko, Varjosalo, Markku T, del Río Hernández, Armando E
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2018
Aiheet:
Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322388/
https://ncbi.nlm.nih.gov/pubmed/30538116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201846557
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