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Tamoxifen mechanically deactivates hepatic stellate cells via the G protein-coupled estrogen receptor
Tamoxifen has been used for many years to target estrogen receptor signalling in breast cancer cells. Tamoxifen is also an agonist of the G protein-coupled estrogen receptor (GPER), a GPCR ubiquitously expressed in tissues that mediates the acute response to estrogens. Here we report that tamoxifen...
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| 出版年: | Oncogene |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6755965/ https://ncbi.nlm.nih.gov/pubmed/30575816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0631-3 |
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