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GPER is a mechanoregulator of pancreatic stellate cells and the tumor microenvironment

The mechanical properties of the tumor microenvironment are emerging as attractive targets for the development of therapies. Tamoxifen, an agonist of the G protein‐coupled estrogen receptor (GPER), is widely used to treat estrogen‐positive breast cancer. Here, we show that tamoxifen mechanically rep...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:EMBO Rep
Hauptverfasser: Cortes, Ernesto, Sarper, Muge, Robinson, Benjamin, Lachowski, Dariusz, Chronopoulos, Antonios, Thorpe, Stephen D, Lee, David A, del Río Hernández, Armando E
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322386/
https://ncbi.nlm.nih.gov/pubmed/30538117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201846556
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