Substrate Rigidity Controls Activation and Durotaxis in Pancreatic Stellate Cells

Pancreatic Ductal Adenocarcinoma (PDAC) is an aggressive malignancy characterised by the presence of extensive desmoplasia, thought to be responsible for the poor response of patients to systemic therapies. Pancreatic stellate cells (PSCs) are key mediators in the production of this fibrotic stroma,...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lachowski, Dariusz, Cortes, Ernesto, Pink, Daniel, Chronopoulos, Antonios, Karim, Saadia A., P. Morton, Jennifer, del Río Hernández, Armando E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451433/
https://ncbi.nlm.nih.gov/pubmed/28566691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02689-x
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados