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Tamoxifen mechanically reprograms the tumor microenvironment via HIF‐1A and reduces cancer cell survival

The tumor microenvironment is fundamental to cancer progression, and the influence of its mechanical properties is increasingly being appreciated. Tamoxifen has been used for many years to treat estrogen‐positive breast cancer. Here we report that tamoxifen regulates the level and activity of collag...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:EMBO Rep
Egile Nagusiak: Cortes, Ernesto, Lachowski, Dariusz, Robinson, Benjamin, Sarper, Muge, Teppo, Jaakko S, Thorpe, Stephen D, Lieberthal, Tyler J, Iwamoto, Kazunari, Lee, David A, Okada‐Hatakeyama, Mariko, Varjosalo, Markku T, del Río Hernández, Armando E
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322388/
https://ncbi.nlm.nih.gov/pubmed/30538116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201846557
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