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Metabolic reprogramming by HIF‐1 activation enhances survivability of human adipose‐derived stem cells in ischaemic microenvironments

OBJECTIVES: Poor cell survival severely limits the beneficial effect of adipose‐derived stem cell (ADSC)‐based therapy for disease treatment and tissue regeneration, which might be caused by the attenuated level of hypoxia‐inducible factor‐1 (HIF‐1) in these cells after having been cultured in 21% a...

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Detalhes bibliográficos
Publicado no:Cell Prolif
Main Authors: Chen, Chang, Tang, Qi, Zhang, Yan, Dai, Minjia, Jiang, Yichen, Wang, Hang, Yu, Mei, Jing, Wei, Tian, Weidong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529110/
https://ncbi.nlm.nih.gov/pubmed/28752896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12363
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