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Metabolic reprogramming by HIF‐1 activation enhances survivability of human adipose‐derived stem cells in ischaemic microenvironments

OBJECTIVES: Poor cell survival severely limits the beneficial effect of adipose‐derived stem cell (ADSC)‐based therapy for disease treatment and tissue regeneration, which might be caused by the attenuated level of hypoxia‐inducible factor‐1 (HIF‐1) in these cells after having been cultured in 21% a...

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Vydáno v:Cell Prolif
Hlavní autoři: Chen, Chang, Tang, Qi, Zhang, Yan, Dai, Minjia, Jiang, Yichen, Wang, Hang, Yu, Mei, Jing, Wei, Tian, Weidong
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529110/
https://ncbi.nlm.nih.gov/pubmed/28752896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12363
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