Simvastatin Enhances the Chondrogenesis But Not the Osteogenesis of Adipose-Derived Stem Cells in a Hyaluronan Microenvironment

Directing adipose-derived stem cells (ADSCs) toward chondrogenesis is critical for ADSC-based articular cartilage regeneration. Simvastatin (SIM) was reported to promote both chondrogenic and osteogenic differentiation of ADSCs by upregulating bone morphogenetic protein-2 (BMP-2). We previously foun...

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Publicado no:Biomedicines
Main Authors: Wu, Shun-Cheng, Chang, Chih-Hsiang, Chang, Ling-Hua, Wu, Che-Wei, Chen, Jhen-Wei, Chen, Chung-Hwan, Lin, Yi-Shan, Chang, Je-Ken, Ho, Mei-Ling
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8156330/
https://ncbi.nlm.nih.gov/pubmed/34067739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9050559
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