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Alpha-5 Integrin Mediates Simvastatin-Induced Osteogenesis of Bone Marrow Mesenchymal Stem Cells

Simvastatin (SVS) promotes the osteogenic differentiation of mesenchymal stem cells (MSCs) and has been studied for MSC-based bone regeneration. However, the mechanism underlying SVS-induced osteogenesis is not well understood. We hypothesize that α5 integrin mediates SVS-induced osteogenic differen...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Shao, Pei-Lin, Wu, Shun-Cheng, Lin, Zih-Yin, Ho, Mei-Ling, Chen, Chung-Hwan, Wang, Chau-Zen
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6387019/
https://ncbi.nlm.nih.gov/pubmed/30682874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20030506
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