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Induction of OTUD4 by viral infection promotes antiviral responses through deubiquitinating and stabilizing MAVS
The activity and stability of the adapter protein MAVS (also known as VISA, Cardif and IPS-1), which critically mediates cellular antiviral responses, are extensively regulated by ubiquitination. However, the process whereby MAVS is deubiquitinated is unclear. Here, we report that the ovarian tumor...
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| Udgivet i: | Cell Res |
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| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6318273/ https://ncbi.nlm.nih.gov/pubmed/30410068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-018-0107-6 |
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