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Induction of USP25 by viral infection promotes innate antiviral responses by mediating the stabilization of TRAF3 and TRAF6

Host pathogen-recognition receptors detect nucleic acid from invading viruses and initiate a series of signaling pathways that lead to the production of type I interferons (IFNs) and proinflammatory cytokines. Here, we found that a viral infection-induced deubiquitinase (DUB), ubiquitin-specific pro...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Lin, Dandan, Zhang, Man, Zhang, Meng-Xin, Ren, Yujie, Jin, Jie, Zhao, Quanyi, Pan, Zishu, Wu, Min, Shu, Hong-Bing, Dong, Chen, Zhong, Bo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568686/
https://ncbi.nlm.nih.gov/pubmed/26305951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1509968112
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