Induction of OTUD4 by viral infection promotes antiviral responses through deubiquitinating and stabilizing MAVS

The activity and stability of the adapter protein MAVS (also known as VISA, Cardif and IPS-1), which critically mediates cellular antiviral responses, are extensively regulated by ubiquitination. However, the process whereby MAVS is deubiquitinated is unclear. Here, we report that the ovarian tumor...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Res
Prif Awduron: Liuyu, Tianzi, Yu, Keying, Ye, Liya, Zhang, Zhidong, Zhang, Man, Ren, Yujie, Cai, Zeng, Zhu, Qiyun, Lin, Dandan, Zhong, Bo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318273/
https://ncbi.nlm.nih.gov/pubmed/30410068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-018-0107-6
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