Induction of OTUD4 by viral infection promotes antiviral responses through deubiquitinating and stabilizing MAVS

The activity and stability of the adapter protein MAVS (also known as VISA, Cardif and IPS-1), which critically mediates cellular antiviral responses, are extensively regulated by ubiquitination. However, the process whereby MAVS is deubiquitinated is unclear. Here, we report that the ovarian tumor...

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Bibliografiset tiedot
Julkaisussa:Cell Res
Päätekijät: Liuyu, Tianzi, Yu, Keying, Ye, Liya, Zhang, Zhidong, Zhang, Man, Ren, Yujie, Cai, Zeng, Zhu, Qiyun, Lin, Dandan, Zhong, Bo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2018
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318273/
https://ncbi.nlm.nih.gov/pubmed/30410068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-018-0107-6
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