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Common binding sites for cholesterol and neurosteroids on a pentameric ligand-gated ion channel
Cholesterol is an essential component of cell membranes, and is required for mammalian pentameric ligand-gated ion channel (pLGIC) function. Computational studies suggest direct interactions between cholesterol and pLGIC’s but experimental evidence identifying specific binding sites is limited. In t...
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| Publicado no: | Biochim Biophys Acta Mol Cell Biol Lipids |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6311151/ https://ncbi.nlm.nih.gov/pubmed/30471426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2018.11.005 |
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