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Perspectives on In Vitro to In Vivo Extrapolations
Quantitative in vitro to in vivo extrapolation (QIVIVE) is broadly considered a prerequisite bridge from in vitro findings to a dose paradigm. Quality and relevance of cell systems are the first prerequisite for QIVIVE. Information-rich and mechanistic endpoints (biomarkers) improve extrapolations,...
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| Publicado no: | Appl In Vitro Toxicol |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Mary Ann Liebert, Inc., publishers
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6309130/ https://ncbi.nlm.nih.gov/pubmed/31890748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aivt.2016.0026 |
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