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A Computational Workflow for Probabilistic Quantitative in Vitro to in Vivo Extrapolation
A computational workflow was developed to facilitate the process of quantitative in vitro to in vivo extrapolation (QIVIVE), specifically the translation of in vitro concentration-response to in vivo dose-response relationships and subsequent derivation of a benchmark dose value (BMD). The workflow...
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| Publicado no: | Front Pharmacol |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5968095/ https://ncbi.nlm.nih.gov/pubmed/29867507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00508 |
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