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A Workflow for Global Sensitivity Analysis of PBPK Models
Physiologically based pharmacokinetic (PBPK) models have a potentially significant role in the development of a reliable predictive toxicity testing strategy. The structure of PBPK models are ideal frameworks into which disparate in vitro and in vivo data can be integrated and utilized to translate...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Research Foundation
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3128931/ https://ncbi.nlm.nih.gov/pubmed/21772819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2011.00031 |
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