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Reconstruction of Exposure to m-Xylene from Human Biomonitoring Data Using PBPK Modelling, Bayesian Inference, and Markov Chain Monte Carlo Simulation

There are numerous biomonitoring programs, both recent and ongoing, to evaluate environmental exposure of humans to chemicals. Due to the lack of exposure and kinetic data, the correlation of biomarker levels with exposure concentrations leads to difficulty in utilizing biomonitoring data for biolog...

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Main Authors: McNally, Kevin, Cotton, Richard, Cocker, John, Jones, Kate, Bartels, Mike, Rick, David, Price, Paul, Loizou, George
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376947/
https://ncbi.nlm.nih.gov/pubmed/22719759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/760281
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