Reconstruction of Exposure to m-Xylene from Human Biomonitoring Data Using PBPK Modelling, Bayesian Inference, and Markov Chain Monte Carlo Simulation

There are numerous biomonitoring programs, both recent and ongoing, to evaluate environmental exposure of humans to chemicals. Due to the lack of exposure and kinetic data, the correlation of biomarker levels with exposure concentrations leads to difficulty in utilizing biomonitoring data for biolog...

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Detalhes bibliográficos
Main Authors: McNally, Kevin, Cotton, Richard, Cocker, John, Jones, Kate, Bartels, Mike, Rick, David, Price, Paul, Loizou, George
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376947/
https://ncbi.nlm.nih.gov/pubmed/22719759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/760281
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