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Quantitative global sensitivity analysis of a biologically based dose-response pregnancy model for the thyroid endocrine system

A deterministic biologically based dose-response model for the thyroidal system in a near-term pregnant woman and the fetus was recently developed to evaluate quantitatively thyroid hormone perturbations. The current work focuses on conducting a quantitative global sensitivity analysis on this compl...

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Bibliographic Details
Published in:Front Pharmacol
Main Authors: Lumen, Annie, McNally, Kevin, George, Nysia, Fisher, Jeffrey W., Loizou, George D.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4444753/
https://ncbi.nlm.nih.gov/pubmed/26074819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00107
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