PET neuroimaging reveals histone deacetylase dysregulation in schizophrenia

BACKGROUND. Patients with schizophrenia (SCZ) experience chronic cognitive deficits. Histone deacetylases (HDACs) are enzymes that regulate cognitive circuitry; however, the role of HDACs in cognitive disorders, including SCZ, remains unknown in humans. We previously determined that HDAC2 mRNA level...

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Xehetasun bibliografikoak
Argitaratua izan da:J Clin Invest
Egile Nagusiak: Gilbert, Tonya M., Zürcher, Nicole R., Wu, Christine J., Bhanot, Anisha, Hightower, Baileigh G., Kim, Minhae, Albrecht, Daniel S., Wey, Hsiao-Ying, Schroeder, Frederick A., Rodriguez-Thompson, Anais, Morin, Thomas M., Hart, Kamber L., Pellegrini, Amelia M., Riley, Misha M., Wang, Changning, Stufflebeam, Steven M., Haggarty, Stephen J., Holt, Daphne J., Loggia, Marco L., Perlis, Roy H., Brown, Hannah E., Roffman, Joshua L., Hooker, Jacob M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2018
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6307962/
https://ncbi.nlm.nih.gov/pubmed/30530989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI123743
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