[(11)C]PBR28 MR–PET imaging reveals lower regional brain expression of translocator protein (TSPO) in young adult males with autism spectrum disorder

Mechanisms of neuroimmune and mitochondrial dysfunction have been repeatedly implicated in autism spectrum disorder (ASD). To examine these mechanisms in ASD individuals, we measured the in vivo expression of the 18 kDa translocator protein (TSPO), an activated glial marker expressed on mitochondria...

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Publicat a:Mol Psychiatry
Autors principals: Zürcher, N. R., Loggia, M. L., Mullett, J. E., Tseng, C., Bhanot, A., Richey, L., Hightower, B. G., Wu, C., Parmar, A. J., Butterfield, R. I., Dubois, J. M., Chonde, D. B., Izquierdo-Garcia, D., Wey, H. Y., Catana, C., Hadjikhani, N., McDougle, C. J., Hooker, J. M.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8159742/
https://ncbi.nlm.nih.gov/pubmed/32076115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-020-0682-z
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