Neuroepigenetic signatures of age and sex in the living human brain

Age- and sex-related alterations in gene transcription have been demonstrated, however the underlying mechanisms are unresolved. Neuroepigenetic pathways regulate gene transcription in the brain. Here, we measure in vivo expression of the epigenetic enzymes, histone deacetylases (HDACs), across heal...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Gilbert, Tonya M., Zürcher, Nicole R., Catanese, Mary C., Tseng, Chieh-En J., Di Biase, Maria A., Lyall, Amanda E., Hightower, Baileigh G., Parmar, Anjali J., Bhanot, Anisha, Wu, Christine J., Hibert, Matthew L., Kim, Minhae, Mahmood, Umar, Stufflebeam, Steven M., Schroeder, Frederick A., Wang, Changning, Roffman, Joshua L., Holt, Daphne J., Greve, Douglas N., Pasternak, Ofer, Kubicki, Marek, Wey, Hsiao-Ying, Hooker, Jacob M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6610136/
https://ncbi.nlm.nih.gov/pubmed/31270332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11031-0
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