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Plasma and cerebrospinal fluid pharmacokinetics of the Akt inhibitor, perifosine, in a non‑human primate model
PURPOSE: Central nervous system tumors are histologically and biologically heterogeneous. Standard treatment for malignant tumors includes surgery, radiation and chemotherapy, yet surgical resection is not always an option and chemotherapeutic agents have limited benefit. Recent investigations have...
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| Publicado en: | Cancer Chemother Pharmacol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6301001/ https://ncbi.nlm.nih.gov/pubmed/25740692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-015-2711-1 |
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