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Plasma and cerebrospinal fluid pharmacokinetics of the Akt inhibitor, perifosine, in a non‑human primate model

PURPOSE: Central nervous system tumors are histologically and biologically heterogeneous. Standard treatment for malignant tumors includes surgery, radiation and chemotherapy, yet surgical resection is not always an option and chemotherapeutic agents have limited benefit. Recent investigations have...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Chemother Pharmacol
Egile Nagusiak: Cole, Diane E., Lester-McCully, Cynthia M., Widemann, Brigitte C., Warren, Katherine E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6301001/
https://ncbi.nlm.nih.gov/pubmed/25740692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-015-2711-1
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