Plasma and cerebrospinal fluid pharmacokinetics of vincristine and vincristine sulfate liposomes injection (VSLI, marqibo®) after intravenous administration in Non-human primates

PURPOSE: Vincristine sulfate liposomes injection (VSLI, Marqibo®) is an FDA approved encapsulated preparation of standard vincristine in sphingomyelin/cholesterol liposomes. Clinical pharmacokinetics show VSLI to be a long-circulating, slow release formulation that is confined to plasma, and prior d...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Invest New Drugs
Egile Nagusiak: Shah, Nirali N., Cole, Diane E., Lester-McCully, Cynthia M., Wayne, Alan S., Warren, Katherine E., Widemann, Brigitte C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6343835/
https://ncbi.nlm.nih.gov/pubmed/26661090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-015-0311-x
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