載入...

TRTH-33. COMPARATIVE PLASMA AND CEREBROSPINAL FLUID PHARMACOKINETICS OF BRAF AND MEK INHIBITORS IN A NONHUMAN PRIMATE MODEL

PURPOSE: BRAF(V600E) mutations are present in several pediatric CNS tumors, particularly pilocytic astrocytomas, gangliogliomas and pleomorphic xanthochromic astrocytomas. Several BRAF inhibitors are under clinical investigation, alone and in combination with MEK inhibitors. To guide the clinical de...

全面介紹

Na minha lista:
書目詳細資料
發表在:Neuro Oncol
Main Authors: Rodgers, Louis, M Lester McCully, Cynthia, Gross, Andrea, Peer, Cody, Cruz, Rafael, Figg, William D, Widemann, Brigette, Warren, Katherine
格式: Artigo
語言:Inglês
出版: Oxford University Press 2017
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475218/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.243
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!