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The plasma and cerebrospinal fluid pharmacokinetics of the platinum analog satraplatin after intravenous administration in non-human primates

BACKGROUND: Satraplatin is an orally bioavailable platinum analog with preclinical activity in cisplatin resistant models and clinical activity in adults with refractory cancers. The cerebrospinal fluid (CSF) penetration of cisplatin and carboplatin in non-human primates (NHP) is limited (3.7 and 2....

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書目詳細資料
發表在:Cancer Chemother Pharmacol
Main Authors: Marcus, Leigh, Murphy, Robert, Fox, Elizabeth, McCully, Cynthia, Cruz, Raphael, Warren, Katherine E., Meyer, Thorsten, McNiff, Edward, Balis, Frank M., Widemann, Brigitte C.
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300136/
https://ncbi.nlm.nih.gov/pubmed/21706317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-011-1659-z
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