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The serum and cerebrospinal fluid pharmacokinetics of anakinra after intravenous administration to non-human primates
Anakinra improves the central nervous system manifestations of neonatal-onset multisystem inflammatory disease, which is mediated by IL-1β oversecretion. The cerebrospinal fluid (CSF) penetration of the IL-1 receptor antagonist anakinra was studied in rhesus monkeys after intravenous doses of 3 and...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2887614/ https://ncbi.nlm.nih.gov/pubmed/20421138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2010.03.022 |
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