High-resolution deconstruction of evolution induced by chemotherapy treatments in breast cancer xenografts

The processes by which tumors evolve are essential to the efficacy of treatment, but quantitative understanding of intratumoral dynamics has been limited. Although intratumoral heterogeneity is common, quantification of evolution is difficult from clinical samples because treatment replicates cannot...

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Foilsithe in:Sci Rep
Main Authors: Kim, Hyunsoo, Kumar, Pooja, Menghi, Francesca, Noorbakhsh, Javad, Cerveira, Eliza, Ryan, Mallory, Zhu, Qihui, Ananda, Guruprasad, George, Joshy, Chen, Henry C., Mockus, Susan, Zhang, Chengsheng, Yang, Yan, Keck, James, Karuturi, R. Krishna Murthy, Bult, Carol J., Lee, Charles, Liu, Edison T., Chuang, Jeffrey H.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2018
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6298990/
https://ncbi.nlm.nih.gov/pubmed/30560892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36184-8
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