The tandem duplicator phenotype as a distinct genomic configuration in cancer

Next-generation sequencing studies have revealed genome-wide structural variation patterns in cancer, such as chromothripsis and chromoplexy, that do not engage a single discernable driver mutation, and whose clinical relevance is unclear. We devised a robust genomic metric able to identify cancers...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Menghi, Francesca, Inaki, Koichiro, Woo, XingYi, Kumar, Pooja A., Grzeda, Krzysztof R., Malhotra, Ankit, Yadav, Vinod, Kim, Hyunsoo, Marquez, Eladio J., Ucar, Duygu, Shreckengast, Phung T., Wagner, Joel P., MacIntyre, George, Murthy Karuturi, Krishna R., Scully, Ralph, Keck, James, Chuang, Jeffrey H., Liu, Edison T.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855596/
https://ncbi.nlm.nih.gov/pubmed/27071093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1520010113
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