Functional chromatin features are associated with structural mutations in cancer

BACKGROUND: Structural mutations (SMs) play a major role in cancer development. In some cancers, such as breast and ovarian, DNA double-strand breaks (DSBs) occur more frequently in transcribed regions, while in other cancer types such as prostate, there is a consistent depletion of breakpoints in t...

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Bibliografiske detaljer
Udgivet i:BMC Genomics
Main Authors: Grzeda, Krzysztof R, Royer-Bertrand, Beryl, Inaki, Koichiro, Kim, Hyunsoo, Hillmer, Axel M, Liu, Edison T, Chuang, Jeffrey H
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253614/
https://ncbi.nlm.nih.gov/pubmed/25417144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-1013
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