Genomic data analysis workflows for tumors from patient-derived xenografts (PDXs): challenges and guidelines

BACKGROUND: Patient-derived xenograft (PDX) models are in vivo models of human cancer that have been used for translational cancer research and therapy selection for individual patients. The Jackson Laboratory (JAX) PDX resource comprises 455 models originating from 34 different primary sites (as of...

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Dettagli Bibliografici
Pubblicato in:BMC Med Genomics
Autori principali: Woo, Xing Yi, Srivastava, Anuj, Graber, Joel H., Yadav, Vinod, Sarsani, Vishal Kumar, Simons, Al, Beane, Glen, Grubb, Stephen, Ananda, Guruprasad, Liu, Rangjiao, Stafford, Grace, Chuang, Jeffrey H., Airhart, Susan D., Karuturi, R. Krishna Murthy, George, Joshy, Bult, Carol J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
Soggetti:
Technical Advance
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6604205/
https://ncbi.nlm.nih.gov/pubmed/31262303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-019-0551-2
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