Genomic data analysis workflows for tumors from patient-derived xenografts (PDXs): challenges and guidelines

BACKGROUND: Patient-derived xenograft (PDX) models are in vivo models of human cancer that have been used for translational cancer research and therapy selection for individual patients. The Jackson Laboratory (JAX) PDX resource comprises 455 models originating from 34 different primary sites (as of...

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Bibliografiske detaljer
Udgivet i:BMC Med Genomics
Main Authors: Woo, Xing Yi, Srivastava, Anuj, Graber, Joel H., Yadav, Vinod, Sarsani, Vishal Kumar, Simons, Al, Beane, Glen, Grubb, Stephen, Ananda, Guruprasad, Liu, Rangjiao, Stafford, Grace, Chuang, Jeffrey H., Airhart, Susan D., Karuturi, R. Krishna Murthy, George, Joshy, Bult, Carol J.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Technical Advance
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6604205/
https://ncbi.nlm.nih.gov/pubmed/31262303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-019-0551-2
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