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Gain of function conferred by selenocysteine: catalytic enhancement of one‐electron transfer reactions by thioredoxin reductase

Selenocysteine (Sec) is the 21st amino acid in the genetic code and it is present in a small number of proteins where it replaces the much more commonly used amino acid cysteine (Cys). It is both more complicated and bioenergetically costly to insert Sec into a protein in comparison to Cys, and this...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Barber, Drew R., Hondal, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6295889/
https://ncbi.nlm.nih.gov/pubmed/30052295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3480
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