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Resolution of oxidative stress by thioredoxin reductase: Cysteine versus selenocysteine
Thioredoxin reductase (TR) catalyzes the reduction of thioredoxin (TRX), which in turn reduces mammalian typical 2-Cys peroxiredoxins (PRXs 1–4), thiol peroxidases implicated in redox homeostasis and cell signaling. Typical 2-Cys PRXs are inactivated by hyperoxidation of the peroxidatic cysteine to...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3949094/ https://ncbi.nlm.nih.gov/pubmed/24624337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2014.01.021 |
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