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No Selenium Required: Reactions Catalyzed By Mammalian Thioredoxin Reductase That Are Independent of a Selenocysteine Residue.
Mammalian thioredoxin reductase (TR) contains a rare selenocysteine (Sec) residue in a conserved redox active tetrapeptide of sequence Gly-Cys(1)-Sec(2)-Gly. The high chemical reactivity of the Sec residue is thought to confer broad substrate specificity to the enzyme. In addition to utilizing thior...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2754045/ https://ncbi.nlm.nih.gov/pubmed/19366212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi802146w |
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