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Selenium as an Electron Acceptor during the Catalytic Mechanism of Thioredoxin Reductase

[Image: see text] Mammalian thioredoxin reductase (TR) is a pyridine nucleotide disulfide oxidoreductase that uses the rare amino acid selenocysteine (Sec) in place of the more commonly used amino acid cysteine (Cys) in the redox-active tetrapeptide Gly-Cys-Sec-Gly motif to catalyze thiol/disulfide...

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Detalles Bibliográficos
Main Authors: Lothrop, Adam P., Snider, Gregg W., Ruggles, Erik L., Patel, Amar S., Lees, Watson J., Hondal, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2014
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957198/
https://ncbi.nlm.nih.gov/pubmed/24422500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400658g
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