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Selenocysteine Confers Resistance to Inactivation by Oxidation in Thioredoxin Reductase: Comparison of Selenium and Sulfur Enzymes()

Mammalian thioredoxin reductase (TR) is a selenocysteine (Sec)-containing homodimeric pyridine nucleotide oxidoreductase which catalyzes the reduction of oxidized thioredoxin. We have previously demonstrated the full-length mitochondrial mammalian TR (mTR3) enzyme to be resistant to inactivation fro...

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Detalhes bibliográficos
Main Authors: Snider, Gregg W., Ruggles, Erik, Khan, Nadeem, Hondal, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760785/
https://ncbi.nlm.nih.gov/pubmed/23865454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400462j
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