CRISPR-C: circularization of genes and chromosome by CRISPR in human cells

Extrachromosomal circular DNA (eccDNA) and ring chromosomes are genetic alterations found in humans with genetic disorders. However, there is a lack of genetic engineering tools to recapitulate and study the biogenesis of eccDNAs. Here, we created a dual-fluorescence biosensor cassette, which upon t...

全面介紹

Na minha lista:
書目詳細資料
發表在:Nucleic Acids Res
Main Authors: Møller, Henrik Devitt, Lin, Lin, Xiang, Xi, Petersen, Trine Skov, Huang, Jinrong, Yang, Luhan, Kjeldsen, Eigil, Jensen, Uffe Birk, Zhang, Xiuqing, Liu, Xin, Xu, Xun, Wang, Jian, Yang, Huanming, Church, George M, Bolund, Lars, Regenberg, Birgitte, Luo, Yonglun
格式: Artigo
語言:Inglês
出版: Oxford University Press 2018
主題:
Methods Online
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294522/
https://ncbi.nlm.nih.gov/pubmed/30551175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky767
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍