CRISPR-C: circularization of genes and chromosome by CRISPR in human cells

Extrachromosomal circular DNA (eccDNA) and ring chromosomes are genetic alterations found in humans with genetic disorders. However, there is a lack of genetic engineering tools to recapitulate and study the biogenesis of eccDNAs. Here, we created a dual-fluorescence biosensor cassette, which upon t...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Møller, Henrik Devitt, Lin, Lin, Xiang, Xi, Petersen, Trine Skov, Huang, Jinrong, Yang, Luhan, Kjeldsen, Eigil, Jensen, Uffe Birk, Zhang, Xiuqing, Liu, Xin, Xu, Xun, Wang, Jian, Yang, Huanming, Church, George M, Bolund, Lars, Regenberg, Birgitte, Luo, Yonglun
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
Matèries:
Methods Online
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294522/
https://ncbi.nlm.nih.gov/pubmed/30551175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky767
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars