CRISPR-C: circularization of genes and chromosome by CRISPR in human cells

Extrachromosomal circular DNA (eccDNA) and ring chromosomes are genetic alterations found in humans with genetic disorders. However, there is a lack of genetic engineering tools to recapitulate and study the biogenesis of eccDNAs. Here, we created a dual-fluorescence biosensor cassette, which upon t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nucleic Acids Res
Egile Nagusiak: Møller, Henrik Devitt, Lin, Lin, Xiang, Xi, Petersen, Trine Skov, Huang, Jinrong, Yang, Luhan, Kjeldsen, Eigil, Jensen, Uffe Birk, Zhang, Xiuqing, Liu, Xin, Xu, Xun, Wang, Jian, Yang, Huanming, Church, George M, Bolund, Lars, Regenberg, Birgitte, Luo, Yonglun
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2018
Gaiak:
Methods Online
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294522/
https://ncbi.nlm.nih.gov/pubmed/30551175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky767
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