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Extrachromosomal circular DNA is common in yeast

Examples of extrachromosomal circular DNAs (eccDNAs) are found in many organisms, but their impact on genetic variation at the genome scale has not been investigated. We mapped 1,756 eccDNAs in the Saccharomyces cerevisiae genome using Circle-Seq, a highly sensitive eccDNA purification method. Yeast...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Møller, Henrik D., Parsons, Lance, Jørgensen, Tue S., Botstein, David, Regenberg, Birgitte
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475933/
https://ncbi.nlm.nih.gov/pubmed/26038577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1508825112
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