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Role of the C‐terminus of SUR in the differential regulation of β‐cell and cardiac K(ATP) channels by MgADP and metabolism

KEY POINTS: β‐Cell K(ATP) channels are partially open in the absence of metabolic substrates, whereas cardiac K(ATP) channels are closed. Using cloned channels heterologously expressed in Xenopus oocytes we measured the effect of MgADP on the MgATP concentration–inhibition curve immediately after pa...

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Dades bibliogràfiques
Publicat a:J Physiol
Autors principals: Vedovato, Natascia, Rorsman, Olof, Hennis, Konstantin, Ashcroft, Frances M., Proks, Peter
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6292810/
https://ncbi.nlm.nih.gov/pubmed/30179258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP276708
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