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Activation of the K(ATP) channel by Mg-nucleotide interaction with SUR1

The mechanism of adenosine triphosphate (ATP)-sensitive potassium (K(ATP)) channel activation by Mg-nucleotides was studied using a mutation (G334D) in the Kir6.2 subunit of the channel that renders K(ATP) channels insensitive to nucleotide inhibition and has no apparent effect on their gating. K(AT...

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Detalles Bibliográficos
Main Authors: Proks, Peter, de Wet, Heidi, Ashcroft, Frances M.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947056/
https://ncbi.nlm.nih.gov/pubmed/20876358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201010475
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