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Hypusine, a polyamine-derived amino acid critical for eukaryotic translation

The natural amino acid hypusine (N(ϵ)-4-amino-2-hydroxybutyl(lysine)) is derived from the polyamine spermidine, and occurs only in a single family of cellular proteins, eukaryotic translation factor 5A (eIF5A) isoforms. Hypusine is formed by conjugation of the aminobutyl moiety of spermidine to a sp...

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Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Park, Myung Hee, Wolff, Edith C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290153/
https://ncbi.nlm.nih.gov/pubmed/30257869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.TM118.003341
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