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Hypusine modification for growth is the major function of spermidine in Saccharomyces cerevisiae polyamine auxotrophs grown in limiting spermidine

Spermidine and its derivative, hypusinated eIF5A, are essential for the growth of Saccharomyces cerevisiae. Very low concentrations of spermidine (10(−8) M) are sufficient for the growth of S. cerevisiae polyamine auxotrophs (spe1Δ, spe2Δ, and spe3Δ). Under these conditions, even though the growth r...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Chattopadhyay, Manas K., Park, Myung Hee, Tabor, Herbert
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373341/
https://ncbi.nlm.nih.gov/pubmed/18451031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710970105
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