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Hypusine modification for growth is the major function of spermidine in Saccharomyces cerevisiae polyamine auxotrophs grown in limiting spermidine

Spermidine and its derivative, hypusinated eIF5A, are essential for the growth of Saccharomyces cerevisiae. Very low concentrations of spermidine (10(−8) M) are sufficient for the growth of S. cerevisiae polyamine auxotrophs (spe1Δ, spe2Δ, and spe3Δ). Under these conditions, even though the growth r...

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Bibliografske podrobnosti
Main Authors: Chattopadhyay, Manas K., Park, Myung Hee, Tabor, Herbert
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373341/
https://ncbi.nlm.nih.gov/pubmed/18451031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710970105
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