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Hypusine modification for growth is the major function of spermidine in Saccharomyces cerevisiae polyamine auxotrophs grown in limiting spermidine
Spermidine and its derivative, hypusinated eIF5A, are essential for the growth of Saccharomyces cerevisiae. Very low concentrations of spermidine (10(−8) M) are sufficient for the growth of S. cerevisiae polyamine auxotrophs (spe1Δ, spe2Δ, and spe3Δ). Under these conditions, even though the growth r...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2373341/ https://ncbi.nlm.nih.gov/pubmed/18451031 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710970105 |
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