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The Post-Translational Synthesis of a Polyamine-Derived Amino Acid, Hypusine, in the Eukaryotic Translation Initiation Factor 5A (eIF5A)
The eukaryotic translation initiation factor 5A (eIF5A) is the only cellular protein that contains the unique polyamine-derived amino acid, hypusine [N(ε)-(4-amino-2-hydroxybutyl) lysine]. Hypusine is formed in eIF5A by a novel post-translational modification reaction that involves two enzymatic ste...
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2006
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2494880/ https://ncbi.nlm.nih.gov/pubmed/16452303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jb/mvj034 |
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