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Amino acid substrates impose polyamine, eIF5A, or hypusine requirement for peptide synthesis

Whereas ribosomes efficiently catalyze peptide bond synthesis by most amino acids, the imino acid proline is a poor substrate for protein synthesis. Previous studies have shown that the translation factor eIF5A and its bacterial ortholog EF-P bind in the E site of the ribosome where they contact the...

詳細記述

保存先:
書誌詳細
出版年:Nucleic Acids Res
主要な著者: Shin, Byung-Sik, Katoh, Takayuki, Gutierrez, Erik, Kim, Joo-Ran, Suga, Hiroaki, Dever, Thomas E.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737446/
https://ncbi.nlm.nih.gov/pubmed/28637321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx532
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