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Amino acid substrates impose polyamine, eIF5A, or hypusine requirement for peptide synthesis
Whereas ribosomes efficiently catalyze peptide bond synthesis by most amino acids, the imino acid proline is a poor substrate for protein synthesis. Previous studies have shown that the translation factor eIF5A and its bacterial ortholog EF-P bind in the E site of the ribosome where they contact the...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5737446/ https://ncbi.nlm.nih.gov/pubmed/28637321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx532 |
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