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Neuronal growth and survival mediated by eIF5A, a polyamine-modified translation initiation factor
Eukaryotic translation initiation factor 5A (eIF5A), the only known protein containing the polyamine-derived amino acid hypusine, modulates protein synthesis. We show that neurotrophic and neuroprotective actions of nerve growth factor (NGF) are mediated by hypusinated eIF5A, which can account for t...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1820731/ https://ncbi.nlm.nih.gov/pubmed/17360499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611609104 |
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