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The Role of Polyamines in Supporting Growth of Mammalian Cells Is Mediated through Their Requirement for Translation Initiation and Elongation

Polyamines are essential cell constituents whose depletion results in growth cessation. Here we have investigated potential mechanisms of action of polyamines in supporting mammalian cell proliferation. We demonstrate that polyamines regulate translation both at the initiation and at the elongation...

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Autori principali: Landau, Guy, Bercovich, Zippi, Park, Myung Hee, Kahana, Chaim
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857121/
https://ncbi.nlm.nih.gov/pubmed/20181941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.106419
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