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Hypusine, a polyamine-derived amino acid critical for eukaryotic translation
The natural amino acid hypusine (N(ϵ)-4-amino-2-hydroxybutyl(lysine)) is derived from the polyamine spermidine, and occurs only in a single family of cellular proteins, eukaryotic translation factor 5A (eIF5A) isoforms. Hypusine is formed by conjugation of the aminobutyl moiety of spermidine to a sp...
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| Pubblicato in: | J Biol Chem |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6290153/ https://ncbi.nlm.nih.gov/pubmed/30257869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.TM118.003341 |
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